RNA Structural Motif Classification Grammars:
Context-Free and Context-Sensitive (Pseudoknot) Parsing of
RNA Secondary Structure.
Shape or structure, rather than nucleotide
sequence is often more important in
determining RNA molecular function. Sequence-homology
comparisons, the tools most
widely used today such as MSA methods and BLAST can not match the actual structures
RNA’s of a specific
family may form. The theoretical and practical methods presented here search
and match structure rather than looking for sequence to sequence homology.
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Updated: June 1, 2009